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Of all the deteriorative reactions occurring in foods, the Maillard reaction may well prove to be one of the two or three that has received, and will. If you're a regular reader of Serious Eats, you've definitely seen us refer to the Maillard reaction time and again. That's because the Maillard. Maillard reaction is the chemical reaction which occurs between amino acids and reducing sugars in the presence of heat that results the browning of food while forming new aromas and flavors.


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InAmerican chemist The maillard reaction E Hodge published a mechanism for the different steps of the reaction, categorising its stages and identifying a range of the different products produced as a result of these.

He identified the first stage as being the reaction between the sugar and the amino the maillard reaction this produced a glycosylamine compound, which in the second step rearranged to produce a ketosamine. The final stage consists of this the maillard reaction reacting in a number of ways to produce several different compounds, which can themselves react to produce further products.

Melanoidins are one of the potential end products.

Maillard reaction - Wikipedia

These are long, polymeric compounds, which act as brown pigments, giving the cooked food its brown colouration. We propose that proteomics approaches, particularly bottom-up proteomics, will play a significant role in analyses of clinical samples leading to the identification of new markers of disease development and progression.

This complex reaction not only occurs in virtually all heat processed and stored foods but also takes place in the paper, 2 textile, 2 and biopharmaceutical industries. In the body, glycation — the reaction of glucose or its autoxidation products with amines, amino acids, peptides, and proteins — is generally considered the first step in this complex reaction.

Apart from ocular diseases, whose correlation with Maillard chemistry has been more recently studied, the formation of AGEs has also proven to contribute to a wide range of human diseases that include diabetic complicationsthe maillard reaction fibrosisand neurodegeneration.

Receptor systems in the body have been suggested to have the maillard reaction to remove glycation-modified molecules, such as AGEs, to eliminate their effects.

Food Chemistry – The Maillard Reaction | Compound Interest

Advanced glycation in numerous different locations within the eye can prove detrimental. In the corneawhose endothelial cells have been known to express RAGE and the maillard reaction, the accumulation of AGEs is associated with thickened corneal stroma, corneal edema, and morphological changes within patients with diabetes.

Within the lens, Maillard chemistry has been studied extensively in the context of cataract formation. Advanced glycation is known to alter fiber membrane integrity in the lens, and dicarbonyl compounds are known to cause increased the maillard reaction formation within the lens.


This effect is exacerbated by both diabetes and aging. Furthermore, it is thought that AGE-inhibiting compounds are effective in preventing cataract formation in diabetics.